Discovery Projects - Grant ID: DP160103683

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP160103683

Funding Status
Closed

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Funded Activity Summary

Developing the Dunnart as a Model Species for Marsupial Research. The project aims to develop a marsupial model capable of genome manipulations to take our understanding of marsupial biology to the next level. In doing so, the project would produce the first comprehensive transcriptome data defining early cell lineage specification in a marsupial. Combined with similar data from mouse and human, it would enable us to examine diversity in early mammals. In addition, it would identify cohorts of genes with fundamental roles in differentiation of the earliest cell lineages: trophoblast, pluriblast and hypoblast. The project may identify maternally localised transcripts with a marsupial-specific role in trophoblast–pluriblast specification, giving new insights into the fundamental pathways maintaining pluripotency in mammals and the evolution of the mammalian genome.

Funded Activity Details

Start Date: 01-01-2016

End Date: 31-12-2019

Funding Scheme: Discovery Projects

Funding Amount: $682,100.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Developmental Genetics (incl. Sex Determination) | Evolution of Developmental Systems | Genome Structure and Regulation | Genetics

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |

Other Keywords

Developmental Genetics (incl. Sex Determination) | Evolution of Developmental Systems | Expanding Knowledge in the Biological Sciences | Genetics | Genome Structure and Regulation

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