Discovery Projects - Grant ID: DP160102680

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP160102680

Funding Status
Closed

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Funded Activity Summary

How does Clostridium perfringens carry multiple closely related plasmids? The project aims to determine how bacteria are able to replicate and maintain multiple copies of very closely related extrachromosomal elements or plasmids in the same cell. These plasmids are important as they encode toxin genes and antibiotic resistance genes. The project proposes to examine two fundamental hypotheses that are postulated to explain this novel phenomenon. The anticipated outcome of the project is the advancement of fundamental knowledge of how bacteria that cause disease in food-production animals can maintain the genetic elements that enable them to cause these diseases. This would contribute to our understanding of the epidemiology of these economically significant animal pathogens and may support the development of new methods of prevention or treatment.

Funded Activity Details

Start Date: 08-06-2016

End Date: 31-12-2018

Funding Scheme: Discovery Projects

Funding Amount: $394,100.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Microbial Genetics | Microbiology

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |

Other Keywords

Expanding Knowledge in the Biological Sciences | Microbial Genetics | Microbiology

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