Discovery Projects - Grant ID: DP160100647

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP160100647

Funding Status
Closed

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Funded Activity Summary

A novel microtubule severing protein involved in male germ cell biology. The project aims to better understand the cellular and biochemical mechanisms underlying a key component of male fertility. Microtubules are a fundamental component of all cells. A mechanism that is increasingly recognised as essential for microtubules regulation is severing. It has been discovered that an uncharacterised microtubule severing protein, KATNAL2, has a key role in male germ cell development. This project aims to define the mechanisms underlying KATNAL2 function in the male germ line. It is expected that these data will generate a comprehensive picture of KATNAL2 function and provide foundation data of relevance across multiple species and tissues. In the longer term, it may also reveal a rational strategy for fertility enhancement or suppression.

Funded Activity Details

Start Date: 14-01-2016

End Date: 31-12-2018

Funding Scheme: Discovery Projects

Funding Amount: $398,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Paediatrics and Reproductive Medicine | Reproduction | Animal Reproduction | Cell Development, Proliferation and Death

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |

Other Keywords

Animal Reproduction | Cell Development, Proliferation and Death | Expanding Knowledge in the Biological Sciences | Paediatrics and Reproductive Medicine | Reproduction

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