Discovery Projects - Grant ID: DP160100573

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP160100573

Funding Status
Closed

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Funded Activity Summary

Evolutionary origin of stem cells and the emergence of animal complexity. The project aims to decipher the fundamental mechanisms governing stem cell specification and formation. All animals rely on stem cells to replenish, repair and regenerate tissues. Stem cells are also often a conduit to malignant tumours. This project seeks to uncover the rules governing stem cell formation through the study of a simple and ancient animal – the marine sponge Amphimedon queenslandica. The project plans to combine insights from the simple, experimentally-tractable sponge stem cell system with existing knowledge of stem cell specification in humans and other animals, to reveal the essential features of stem cell formation. These insights may inform future pursuits to generate, control and use stem cells in cancer and regenerative medicines.

Funded Activity Details

Start Date: 01-01-2016

End Date: 31-12-2019

Funding Scheme: Discovery Projects

Funding Amount: $506,100.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Evolution of Developmental Systems | Molecular Evolution | Invertebrate Biology | Evolutionary Biology

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences | Marine Flora, Fauna and Biodiversity | Fisheries - Aquaculture not elsewhere classified |

Other Keywords

Evolution of Developmental Systems | Evolutionary Biology | Expanding Knowledge in the Biological Sciences | Fisheries - Aquaculture not elsewhere classified | Invertebrate Biology | Marine Flora, Fauna and Biodiversity | Molecular Evolution

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