Discovery Projects - Grant ID: DP160100107

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP160100107

Funding Status
Closed

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

How scissors learn to glue: the catalysis of ligation by proteases. This project proposes to study protein-cutting enzymes from plants that are drawn into biosyntheses where they paradoxically perform protein-joining (ligation) reactions. Enzymes are everywhere, from detergents to digestion to detoxifying drugs. Industry uses artificial evolution to improve enzymes or create enzymes with new activities. By exploring the changes that allowed one such cutting enzyme to ligate, the knowledge acquired may enable protein engineering to develop designer enzymes with enhanced or suppressed ligating ability. Although protein evolution can be studied with artificial systems, natural systems are extremely valuable. Insights from studying this natural evolution of ligation may test hypotheses developed with data from artificial evolution.

Funded Activity Details

Start Date: 01-01-2016

End Date: 31-12-2018

Funding Scheme: Discovery Projects

Funding Amount: $355,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Plant Cell and Molecular Biology | Plant Biology |

ANZSRC Socio-Economic Objective (SEO)

Summer Grains and Oilseeds not elsewhere classified | Plant Production and Plant Primary Products not elsewhere classified | Plant Extract Crops (e.g. Pyrethrum, Jojoba)

Other Keywords

Plant Biology | Plant Cell and Molecular Biology | Plant Extract Crops (e.g. Pyrethrum, Jojoba) | Plant Production and Plant Primary Products not elsewhere classified | Summer Grains and Oilseeds not elsewhere classified

Related Links