Discovery Projects - Grant ID: DP160100019

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP160100019

Funding Status
Closed

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Funded Activity Summary

In vivo mechano-microscopy: a discovery platform for cell mechanics. This project aims to develop a platform for quantitative 3-D imaging of cell elasticity in tissue which may make possible new discoveries in cell mechanics. Mechanical properties, in concert with chemical properties, act to determine the function and behaviour of cells, and play a vital role in diseases such as cancer. Measurement of the mechanical properties of the cell in its native tissue environment, currently not possible, could accelerate the understanding of cell mechanics. This project plans to develop in vivo mechano-microscopy by combining innovations in optical microscopy, micro-mechanical loading, and computational methods. It then plans to demonstrate its capability by producing the first 3-D elasticity maps of skeletal muscle cells in living animals.

Funded Activity Details

Start Date: 01-01-2016

End Date: 31-12-2020

Funding Scheme: Discovery Projects

Funding Amount: $667,300.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biomedical Instrumentation | Optical Physics | Optical Physics not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

Skeletal System and Disorders (incl. Arthritis) | Clinical Health (Organs, Diseases and Abnormal Conditions) not elsewhere classified | Expanding Knowledge in the Biological Sciences |

Other Keywords

Biomedical Instrumentation | Clinical Health (Organs, Diseases and Abnormal Conditions) not elsewhere classified | Expanding Knowledge in the Biological Sciences | Optical Physics | Optical Physics not elsewhere classified | Skeletal System and Disorders (incl. Arthritis)

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