Discovery Projects - Grant ID: DP150104503

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP150104503

Funding Status
Closed

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Funded Activity Summary

A study into post-translational modifications on adaptive immunity. Using proteomics, structural biology and cellular immunology, this project aims to provide a greater understanding of the impact of PTMs on the immune system. The immune system combats pathogens by mounting T-cell responses against foreign antigens present in infected cells. However, T-cells activated by self-antigens that are inadvertently presented by healthy cells can cause aberrant T-cell reactivity and disease. Post-translational modifications (PTMs) are common in the host's proteins, but surprisingly little is known about their effect on T-cell immunity.

Funded Activity Details

Start Date: 01-01-2015

End Date: 20-02-2018

Funding Scheme: Discovery Projects

Funding Amount: $422,100.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Immunology | Proteomics and Intermolecular Interactions (excl. Medical Proteomics) | Biochemistry and Cell Biology | Structural Biology (incl. Macromolecular Modelling)

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |

Other Keywords

Biochemistry and Cell Biology | Cellular Immunology | Expanding Knowledge in the Biological Sciences | Proteomics and Intermolecular Interactions (excl. Medical Proteomics) | Structural Biology (incl. Macromolecular Modelling)

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