Discovery Projects - Grant ID: DP150104358

Funded Activity Summary

Harnessing the potential of metals in biocatalysis. The project aims to use an integrated, multi-disciplinary approach to study the properties of a group of related but functionally diverse enzymes; binuclear metallohydrolases (BMHs). These enzymes are of great relevance to protein engineers aiming to produce potent agents for bioremediation and pharmacologists interested in developing drugs. Elucidating and modulating the mode of action of BMHs is thus our main objective and should provide essential information to fully exploit the potential of these enzymes for practical applications. In particular, understanding how metal ions interact with BMHs and how this contributes to their reactivity is crucial to optimally understand their biotechnological potential.

Funded Activity Details

Start Date: 01-01-2015

End Date: 30-06-2019

Funding Scheme: Discovery Projects

Funding Amount: $429,100.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biocatalysis and Enzyme Technology | Environmental Molecular Engineering of Nucleic Acids and Proteins | Inorganic Chemistry | Bioinorganic Chemistry |

ANZSRC Socio-Economic Objective (SEO)

Land and Water Management of environments not elsewhere classified | Human Pharmaceutical Treatments (e.g. Antibiotics) | Infectious Diseases

Other Keywords

Biocatalysis and Enzyme Technology | Bioinorganic Chemistry | Environmental Molecular Engineering of Nucleic Acids and Proteins | Human Pharmaceutical Treatments (e.g. Antibiotics) | Infectious Diseases | Inorganic Chemistry | Land and Water Management of environments not elsewhere classified

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