Discovery Projects - Grant ID: DP150104321

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP150104321

Funding Status
Closed

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Funded Activity Summary

The role of LIM Kinase 1 in neurons. The aim of this project is to study LIM domain kinase 1 in neuronal function, using cell and mouse models. Unrestricted brain function is essential to one’s wellbeing and the ability to perform normally. Critically contributing to the function of neurons is a cytoskeleton which maintains morphology and function. However, molecular mechanisms underlying cytoskeletal dynamics are poorly understood. LIM domain kinase 1, a key regulator of the actin cytoskeleton decreased with age and its loss associated with deficits in memory and neuronal morphology. This project could reveal fundamental processes regulating and maintaining brain function.

Funded Activity Details

Start Date: 01-04-2015

End Date: 31-03-2018

Funding Scheme: Discovery Projects

Funding Amount: $445,500.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Nervous System | Cell Neurochemistry | Neurosciences

ANZSRC Socio-Economic Objective (SEO)

Nervous System and Disorders | Neurodegenerative Disorders Related to Ageing | Expanding Knowledge in the Biological Sciences |

Other Keywords

Cell Neurochemistry | Cellular Nervous System | Expanding Knowledge in the Biological Sciences | Nervous System and Disorders | Neurodegenerative Disorders Related to Ageing | Neurosciences

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