Discovery Projects - Grant ID: DP150104227

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP150104227

Funding Status
Closed

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Funded Activity Summary

Hydrophobin proteins on the fungal frontline. This project aims to use advanced biophysical techniques to study the role of hydrophobin proteins in three diseases caused by fungi. The specific focus will be on hydrophobins from fungal species that cause severe loss of rice plants, cause invasive growths in humans, and infect the eggs of endangered turtles and result in death of the turtle embryos. Hydrophobins are small fungal proteins that assemble into large biological layers at the boundary between the fungus and the host. This research aims to focus on characterising the structure of the layers, understanding how they form and how they attach to the host tissue. This work may lead to new antifungal strategies aimed at reducing the impact of these devastating fungal infections.

Funded Activity Details

Start Date: 01-01-2015

End Date: 30-04-2018

Funding Scheme: Discovery Projects

Funding Amount: $422,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Mycology | Biochemistry and Cell Biology | Structural Biology (incl. Macromolecular Modelling)

ANZSRC Socio-Economic Objective (SEO)

Control of Pests, Diseases and Exotic Species in Marine Environments | Clinical Health (Organs, Diseases and Abnormal Conditions) not elsewhere classified | Rice |

Other Keywords

Biochemistry and Cell Biology | Clinical Health (Organs, Diseases and Abnormal Conditions) not elsewhere classified | Control of Pests, Diseases and Exotic Species in Marine Environments | Mycology | Rice | Structural Biology (incl. Macromolecular Modelling)

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