Discovery Projects - Grant ID: DP150102569

Funding Activity

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Funded Activity Summary

Nucleolus targeting by negative strand RNA viruses. Negative strand viruses (NSVs) include diverse animal pathogens that represent significant threats to Australian livestock industries and access to export markets. The project aims to investigate the interface formed by NSVs with cellular nucleoli in order to determine roles in viral manipulation of cell biology during infection. This project hopes to address a major gap in knowledge in virology regarding the fundamental biology of NSVs, and is expected to redefine our understanding of the virus-host interactions formed by these important pathogens. By determining the mechanisms of NSV-nucleolus interaction, the project plans to also provide important information for the development of new vaccines/therapeutics for livestock to combat NSVs that target nucleoli.

Funded Activity Details

Start Date: 01-01-2015

End Date: 31-12-2018

Funding Scheme: Discovery Projects

Funding Amount: $443,900.00

Funder: Australian Research Council