Discovery Projects - Grant ID: DP150102428

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP150102428

Funding Status
Closed

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Funded Activity Summary

The role of zinc in synaptic transmission in the central nervous system. By regulating the strength of synaptic transmission between neurons, zinc exerts dynamic control over many physiological processes including memory formation, fear conditioning and movement control. Zinc also controls neuronal cell death pathways. There is currently much controversy about the concentration that zinc reaches in the synaptic cleft and the length of time it remains elevated. By defining these parameters, this project aims to understand which proteins zinc acts upon and the molecular mechanisms by which it exerts its synapse-modulating effects. The outcomes of this project could lead to better understanding of zinc dynamics that could underpin future research into many physiological processes.

Funded Activity Details

Start Date: 01-01-2015

End Date: 30-06-2018

Funding Scheme: Discovery Projects

Funding Amount: $369,900.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Central Nervous System | Biochemistry and Cell Biology | Receptors and Membrane Biology

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |

Other Keywords

Biochemistry and Cell Biology | Central Nervous System | Expanding Knowledge in the Biological Sciences | Receptors and Membrane Biology

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