Discovery Projects - Grant ID: DP150100206

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP150100206

Funding Status
Closed

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Funded Activity Summary

Understanding the cellular cues that direct muscle stem cell specification. The project aims are to identify the metabolic factors that regulate muscle stem cell identity and to examine how changes in the local metabolic environment can influence how stem cells respond to biological perturbations. One of the most important and unresolved issues in skeletal muscle biology is understanding the role of muscle stem cells in the regulation of growth and development, adaptation and plasticity. We have identified that the local skeletal muscle metabolic milieu may regulate the activity of skeletal muscle stem cells. This project could reveal novel mechanisms by which skeletal muscle stem cells can be regulated. This information is crucial for our fundamental understanding of stem cell biology and its future applications.

Funded Activity Details

Start Date: 01-01-2015

End Date: 31-12-2019

Funding Scheme: Discovery Projects

Funding Amount: $733,796.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Biotechnology | Biochemistry and Cell Biology not elsewhere classified | Regenerative Medicine (incl. Stem Cells and Tissue Engineering) |

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Medical and Health Sciences

Other Keywords

Biochemistry and Cell Biology not elsewhere classified | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Medical and Health Sciences | Medical Biotechnology | Regenerative Medicine (incl. Stem Cells and Tissue Engineering)

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