Discovery Projects - Grant ID: DP140104217

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP140104217

Funding Status
Closed

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Funded Activity Summary

Controlling the adhesome to regulate cell fate on biomaterials. Mesenchymal stem cell-based tissue engineering practices are hampered worldwide by the lack of appreciation and understanding of the matrix-mediated cues that must be provided during adhesion and spreading to drive cells to definitive tissue end points. This project will address these knowledge deficiencies by combining high throughput array technologies, a set of tailorable self-assembling biomaterials and real-time biosensors to rapidly, at high resolution, elucidate how mechanotransductive cues determine the fate choice of mesenchymal stem cells, and furthermore, how to manipulate them with smart biomaterial design to achieve desired outcomes for tissue engineering.

Funded Activity Details

Start Date: 01-01-2014

End Date: 31-12-2016

Funding Scheme: Discovery Projects

Funding Amount: $365,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Interactions (incl. Adhesion, Matrix, Cell Wall) | Biomaterials | Regenerative Medicine (incl. Stem Cells and Tissue Engineering) | Biomedical Engineering

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in Engineering | Expanding Knowledge in the Biological Sciences |

Other Keywords

Biomaterials | Biomedical Engineering | Cellular Interactions (incl. Adhesion, Matrix, Cell Wall) | Expanding Knowledge in Engineering | Expanding Knowledge in the Biological Sciences | Regenerative Medicine (incl. Stem Cells and Tissue Engineering)

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