Discovery Projects - Grant ID: DP140102881

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP140102881

Funding Status
Closed

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Funded Activity Summary

Evolution of bacterial pathogenesis. Little is known regarding the specific evolutionary steps involved in the emergence of highly virulent microbial pathogens from benign or mildly virulent populations. The group A streptococcus is exemplary of this vexing problem - a large population reservoir of bacteria exists causing only mild infections and a highly virulent strain emerges causing significant disease and mortality. Utilising an extensive WHO reference collection of group A streptococcus isolates. This project will define the evolutionary events that produced the most significant invasive strain designated M1T1. The M1T1 strain emerged in the mid-1980s, has since disseminated globally, yet the evolutionary sequence of events resulting in this emergence are largely unknown.

Funded Activity Details

Start Date: 01-01-2014

End Date: 31-12-2016

Funding Scheme: Discovery Projects

Funding Amount: $372,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Microbial Genetics | Microbiology | Bacteriology

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |

Other Keywords

Bacteriology | Expanding Knowledge in the Biological Sciences | Microbial Genetics | Microbiology

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