Discovery Projects - Grant ID: DP140102495

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP140102495

Funding Status
Closed

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Funded Activity Summary

Brain Regulation of Reproduction: Challenging the ‘KNDy’ Hypothesis. The brain switches reproduction on and off by changing the frequency of pulses of gonadotrophin releasing hormone. The processes that produce the pulses have been a puzzle for decades but, recently, brain cells that produce three peptides (kisspeptin, neurokinin B, dynorphin), known as ‘KNDy cells’, have been heralded as the ‘missing link’, or even the ‘pulse generator’. Using sheep, this project will challenge the KNDy hypothesis with pheromones and with acute increases in nutrition, two factors that rapidly increase the frequency of gonadotrophin releasing hormone pulses. The outcomes of this research are directly relevant to the optimisation of reproductive management in farm animals, wildlife and humans.

Funded Activity Details

Start Date: 01-01-2014

End Date: 31-12-2018

Funding Scheme: Discovery Projects

Funding Amount: $390,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Zoology | Endocrinology | Animal Neurobiology | Animal Reproduction

ANZSRC Socio-Economic Objective (SEO)

Reproductive System and Disorders | Expanding Knowledge in the Biological Sciences | Sheep - Meat |

Other Keywords

Animal Neurobiology | Animal Reproduction | Endocrinology | Expanding Knowledge in the Biological Sciences | Reproductive System and Disorders | Sheep - Meat | Zoology

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