Discovery Projects - Grant ID: DP140101244

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP140101244

Funding Status
Closed

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Funded Activity Summary

Investigation of a Novel Protein Implicated in Phosphate Metabolism in Bacteria. Phosphate is an important nutrient for all forms of life on Earth. A novel bacterial protein has been identified that appears to be important for the uptake or processing of phosphate, since mutants lacking the protein grow poorly inside certain cells of the human immune system (where phosphate levels are low) and in media containing low phosphate. The aims of this project are: to determine the role of the protein by examining all phosphate containing molecules in our mutants; to determine its location in bacteria and functional domains; to identify other affected genes in our mutants; and, to find proteins that interact with this new protein. This project expects to demonstrate the importance of this protein in phosphate metabolism in bacteria.

Funded Activity Details

Start Date: 01-01-2014

End Date: 31-12-2017

Funding Scheme: Discovery Projects

Funding Amount: $318,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Enzymes | Biochemistry and Cell Biology | Cell Metabolism | Bacteriology

ANZSRC Socio-Economic Objective (SEO)

Infectious Diseases |

Other Keywords

Bacteriology | Biochemistry and Cell Biology | Cell Metabolism | Enzymes | Infectious Diseases

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