Discovery Projects - Grant ID: DP140100977

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP140100977

Funding Status
Closed

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Funded Activity Summary

Gamma delta T cells specific for glycolipid antigens. Gamma delta T cells are an enigmatic component of the immune system that use a unique class of cell surface receptors (gamma delta T cell receptors). Despite having been discovered 30 years ago, very little is known about what these cells recognise and respond to, and therefore what is their function. A population of gamma delta T cells that respond via their T cell receptor to particular forms of lipid molecules presented by an antigen presenting molecule, CD1d has been identified. The aim of this project is to isolate these T cell receptors and investigate the interaction at the molecular level in order to understand the parameters that trigger activation of these cells. This will provide fundamental insight into a key component of the immune system.

Funded Activity Details

Start Date: 01-01-2014

End Date: 31-12-2016

Funding Scheme: Discovery Projects

Funding Amount: $536,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Immunology not elsewhere classified | Immunology |

ANZSRC Socio-Economic Objective (SEO)

Immune System and Allergy | Expanding Knowledge in the Medical and Health Sciences

Other Keywords

Expanding Knowledge in the Medical and Health Sciences | Immune System and Allergy | Immunology | Immunology not elsewhere classified

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