Discovery Projects - Grant ID: DP140100591

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP140100591

Funding Status
Closed

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Funded Activity Summary

Anthocyanin Inhibitors to the Influenza Virus. The increasing resistance of circulating influenza strains to current anti-viral inhibitors has prompted an investigation to screen, design, synthesize and evaluate a new class of natural product based inhibitors to the virus employing novel and innovative mass spectrometry, computational and structural approaches. Preliminary studies reveal they offer benefits in terms of a different mode of binding to influenza neuraminidase, remote from many known resistance mutations, and may have specific practicality against N1 neuraminidase in H1N1 and H5N1 viruses responsible for all pandemics of the 20th and 21st centuries. The research will enable the potential of these inhibitors to be fully assessed at the molecular level for the first time.

Funded Activity Details

Start Date: 01-01-2014

End Date: 31-12-2019

Funding Scheme: Discovery Projects

Funding Amount: $400,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Infectious Agents | Virology | Biological Physics | Microbiology |

ANZSRC Socio-Economic Objective (SEO)

Diagnostic Methods | Expanding Knowledge in the Biological Sciences | Infectious Diseases

Other Keywords

Biological Physics | Diagnostic Methods | Expanding Knowledge in the Biological Sciences | Infectious Agents | Infectious Diseases | Microbiology | Virology

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