Discovery Projects - Grant ID: DP140100385

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP140100385

Funding Status
Closed

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Funded Activity Summary

Understanding the Chemical Processes Involved in the Metabolism of Peptide Hormones. Peptide hormones regulate normal physiological activity in humans, and their over-production causes diseases such as cancer. The aims of this project are: to delineate the chemical processes through which these hormones are produced; to develop inhibitors of enzymes involved in hormone production, and agonists and antagonists of receptors through which the hormones act; and to study the ability of the inhibitors, agonists and antagonists to override and bypass the chemical control mechanisms through which hormone levels are usually maintained at homeostasis. The research is expected to lead to a better fundamental understanding of hormone metabolism, and to underpin the basis for the development of new disease therapies.

Funded Activity Details

Start Date: 01-03-2014

End Date: 31-12-2016

Funding Scheme: Discovery Projects

Funding Amount: $420,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Proteins and Peptides | Physical Organic Chemistry | Medicinal and Biomolecular Chemistry | Biologically Active Molecules

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Chemical Sciences | Cancer and Related Disorders |

Other Keywords

Biologically Active Molecules | Cancer and Related Disorders | Expanding Knowledge in the Chemical Sciences | Medicinal and Biomolecular Chemistry | Physical Organic Chemistry | Proteins and Peptides

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