Discovery Projects - Grant ID: DP120104058

Funding Activity

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Funded Activity Summary

The mechanism of pore formation by Membrane Attack Complex/Perforin-like proteins. Members of the Membrane Attack Complex / Perforin (MACPF) family of proteins are essential for life, playing fundamental roles in immunity, tissue development and neuron formation. This project seeks to understand the basic mechanism of how MACPF proteins can form pores in target cells, a process central for killing in mammalian immunity.

Funded Activity Details

Start Date: 01-01-2012

End Date: 31-12-2014

Funding Scheme: Discovery Projects

Funding Amount: $280,000.00

Funder: Australian Research Council