Discovery Projects - Grant ID: DP1096491

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP1096491

Funding Status
Closed

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Funded Activity Summary

Neuronal functions of the microtubule-associated protein tau in development and ageing. The project uses a combination of transgenic mouse strains characterised by neurodegeneration and senescence-accelerated (SAM) mice, to determine the first steps of the aggregation of the protein tau in degenerating neurons, how absence of tau protects from brain atrophy, and in which physiological processes tau is involved. This project provides the biological foundation for a tau-based therapy of senescence-associated conditions. It provides the biological foundation for developing effective therapies for human neurodegenerative conditions, by preventing tau aggregation and phosphorylation. We will patent new data and expand our existing links to Australian biotech and international pharmaceutical companies.

Funded Activity Details

Start Date: 03-02-2010

End Date: 01-02-2013

Funding Scheme: Discovery Projects

Funding Amount: $555,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Central Nervous System | Biochemistry and Cell Biology | Protein Targeting And Signal Transduction | Cell Neurochemistry

ANZSRC Socio-Economic Objective (SEO)

Nervous system and disorders | Health related to ageing |

Other Keywords

Biochemistry and Cell Biology | Cell Neurochemistry | Central Nervous System | Health related to ageing | Nervous system and disorders | Protein Targeting And Signal Transduction

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