Discovery Projects - Grant ID: DP1094854

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP1094854

Funding Status
Closed

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

Pathogen sensing in systemic inflammatory disease. The initiation, amplification and quenching of an immune response is a carefully orchestrated process that eliminates invading pathogens while minimising collateral damage to host tissues. This research focuses on proteins that restrict immune responses to prevent inflammatory diseases such as rheumatoid arthritis, psoriasis and inflammatory bowel disease. This work will also explore the role of a potassium channel that protects the host from organ failure during an infection, by coupling the energy requirements of mounting an immune response, and organ function. This may have important implications for the management of sepsis, a systemic immune response associated with infection and the leading cause of death in critically ill patients.

Funded Activity Details

Start Date: 01-01-2010

End Date: 31-12-2014

Funding Scheme: Discovery Projects

Funding Amount: $597,970.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Haematology | Cardiorespiratory Medicine and Haematology | Rheumatology And Arthritis | Immunology Not Elsewhere Classified

ANZSRC Socio-Economic Objective (SEO)

Blood disorders | Skeletal system and disorders (incl. arthritis) | Skin and related disorders |

Other Keywords

Blood disorders | Cardiorespiratory Medicine and Haematology | Haematology | Immunology Not Elsewhere Classified | Rheumatology And Arthritis | Skeletal system and disorders (incl. arthritis) | Skin and related disorders

Related Links