Discovery Projects - Grant ID: DP1094768

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP1094768

Funding Status
Closed

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Funded Activity Summary

New Surfaces for the Control of Endothelial Cell Function: Application in the Design of Biocompatible Stents. Using dewetting of thin polymer films, the present proposal will develop new structured biocompatible surfaces with controlled chemistry and topography, which will allow the growth of a normal (non-activated) monolayer of endothelial cells. Sophisticated molecular parameters will be used to assess that endothelial cells maintain their normal quiescent phenotype. The project sets the ground work for the design of improved, more biocompatible structured stents to minimise the abnormal growth of cells on and around the stent, thereby reducing the occurrence of vascular complications. Thus this research could improve the success rate of stents implanted into patients with cardiovascular disease and reduce health costs.

Funded Activity Details

Start Date: 12-08-2010

End Date: 20-09-2013

Funding Scheme: Discovery Projects

Funding Amount: $270,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Polymers | Medical Biotechnology | Biomedical Engineering | Biomaterials

ANZSRC Socio-Economic Objective (SEO)

Biological sciences | Chemical sciences |

Other Keywords

Biological sciences | Biomaterials | Biomedical Engineering | Chemical sciences | Medical Biotechnology | Polymers

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