Discovery Projects - Grant ID: DP1094549

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP1094549

Funding Status
Closed

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Funded Activity Summary

Structure-based discovery of anti-parainfluenza viral agents. Respiratory diseases, for example croup and bronchitis, in children are caused in the main by human parainfluenza viruses (hPIVs) types 1-3. No vaccines or specific antiviral therapy against hPIV infections exist. This project targets an essential protein in the virus' lifecycle. The essential triple role of the protein in virus spread makes it an attractive target for the development of hPIV-specific drugs. This project aims to produce lead-like compounds that inhibit the protein's function and may provide novel drug candidates for further development. Furthermore the role of human host cell-associated carbohydrates in parainfluenza infection will be better understood.

Funded Activity Details

Start Date: 01-01-2010

End Date: 31-12-2012

Funding Scheme: Discovery Projects

Funding Amount: $510,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medicinal and Biomolecular Chemistry | Biological And Medical Chemistry | Medical Virology | Organic Chemical Synthesis

ANZSRC Socio-Economic Objective (SEO)

Infectious diseases | Child health | Treatments (e.g. chemicals, antibiotics) |

Other Keywords

Biological And Medical Chemistry | Child health | Infectious diseases | Medical Virology | Medicinal and Biomolecular Chemistry | Organic Chemical Synthesis | Treatments (e.g. chemicals, antibiotics)

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