Discovery Projects - Grant ID: DP1094497

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP1094497

Funding Status
Closed

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Funded Activity Summary

Synthesis of phosphatidylinositol and inositol polyphosphate derivatives to probe key signalling proteins associated with cell growth and cancer. Health care of an ageing population is a national priority of the community. In order to understand the factors that control cell growth and death in cancer cells signalling proteins can be identified and studied and compared with model systems from quiescent cells. Using phospholipids and inositol polyphosphates attached to 'fishing lines' we can search for, identify and study the function of many of the downstream signalling proteins in activated cancer cells. This will provide the basic information for discovery processes to target specific molecules that inhibit and control the function of the signalling proteins implicated in the growth of cancer cells.

Funded Activity Details

Start Date: 01-01-2010

End Date: 31-03-2014

Funding Scheme: Discovery Projects

Funding Amount: $540,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Organic Chemistry | Organic Chemical Synthesis | Oncology And Carcinogenesis | Protein Targeting And Signal Transduction |

ANZSRC Socio-Economic Objective (SEO)

Health related to ageing | Cancer and related disorders | Chemical sciences

Other Keywords

Cancer and related disorders | Chemical sciences | Health related to ageing | Oncology And Carcinogenesis | Organic Chemical Synthesis | Organic Chemistry | Protein Targeting And Signal Transduction

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