Discovery Projects - Grant ID: DP1094212

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP1094212

Funding Status
Closed

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Funded Activity Summary

New analgesics based on µ-conotoxins: structure-based design of helical mimetics. Diseases in which voltage-gated sodium channels are implicated are contributors to morbidity and mortality in the Australian population, and this project promises to provide new leads for the future development of drugs to treat such diseases, in particular analgesics for the treatment of chronic pain. The generation of these leads will entail the development of new approaches to mimicking key regions of peptides and proteins in drug-like molecules. This is a highly interdisciplinary project, spanning structural biology, molecular design, medicinal chemistry, molecular biology and electrophysiology, and the training of PhD graduates with such broad experience represents another national benefit of the project.

Funded Activity Details

Start Date: 01-01-2010

End Date: 31-12-2013

Funding Scheme: Discovery Projects

Funding Amount: $350,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Biochemistry and Metabolomics | Medical Biochemistry: Proteins And Peptides | Pharmacology Not Elsewhere Classified | Biological And Medical Chemistry |

ANZSRC Socio-Economic Objective (SEO)

Treatments (e.g. chemicals, antibiotics) | Biological sciences | Chemical sciences

Other Keywords

Biological And Medical Chemistry | Biological sciences | Chemical sciences | Medical Biochemistry and Metabolomics | Medical Biochemistry: Proteins And Peptides | Pharmacology Not Elsewhere Classified | Treatments (e.g. chemicals, antibiotics)

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