Discovery Projects - Grant ID: DP1094119

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP1094119

Funding Status
Closed

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Funded Activity Summary

Defining in molecular terms cis-inhibition as a means to inhibit Notch signaling. Normal development of a baby and our health after birth is dependent on how our cells behave. Signals move between cells and within them to tell them what to do. Proteins interacting with other proteins mostly transmit these signals. This research focuses on a protein named Notch and the signals that it transmits. Notch functions in normal processes, such as blood vessel formation; but abnormal signaling causes and/or contributes to pathological situations such as degenerative disease and cancer. We are working to understand how the Notch signal is made and how to control it when it is abnormal. This will allow new medications to be developed to help people who have cancer and other Notch-related illnesses

Funded Activity Details

Start Date: 01-01-2010

End Date: 31-12-2012

Funding Scheme: Discovery Projects

Funding Amount: $390,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Biochemistry: Proteins And Peptides | Biochemistry and Cell Biology | Protein Targeting And Signal Transduction | Genetic Development (Incl. Sex Determination)

ANZSRC Socio-Economic Objective (SEO)

Biological sciences | Organs, diseases and abnormal conditions not elsewhere classified |

Other Keywords

Biochemistry and Cell Biology | Biological sciences | Genetic Development (Incl. Sex Determination) | Medical Biochemistry: Proteins And Peptides | Organs, diseases and abnormal conditions not elsewhere classified | Protein Targeting And Signal Transduction

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