Discovery Projects - Grant ID: DP1093345

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP1093345

Funding Status
Closed

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Funded Activity Summary

Chemistry of the Transport of Nutrient Copper in Biological Cells. Nutrient trace metals such as copper are needed for enzymes by living organisms but are toxic in excess. Defects in copper metabolism cause Menkes and Wilson diseases in humans and there are direct connections to neurodegenerative diseases (eg, Alzheimer, Parkinson, Creutzfeldt-Jakob, motor neuron diseases). It is crucial to understand how healthy cells control toxic but essential copper so that enlightened intervention is possible when disturbances of copper metabolism become pathological. The chemistry of key molecules will be studied to reveal their essential properties and thereby to understand the molecular basis of the copper-linked diseases.

Funded Activity Details

Start Date: 01-01-2010

End Date: 30-06-2014

Funding Scheme: Discovery Projects

Funding Amount: $490,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Bioinorganic Chemistry | Inorganic Chemistry |

ANZSRC Socio-Economic Objective (SEO)

Biological sciences | Chemical sciences

Other Keywords

Bioinorganic Chemistry | Biological sciences | Chemical sciences | Inorganic Chemistry

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