Discovery Projects - Grant ID: DP1093281

Funding Activity

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Funded Activity Summary

Improving immune response to vaccines by selective targeting of epithelial regions with the Nanopatch. Vaccination protects us from infections like measles and flu. In principle, it could protect us from all diseases, even from skin cancer and arthritis. In practice, however, vaccines to diseases like cancer have largely proved ineffective. One problem is that we don't really understand how the body's immune system responds to vaccination. Our aim, therefore, is to investigate changes in the immune system when a vaccine enters the skin, as might happen by injection. Experimenting with laboratory mice and a special vaccine-injecting Nanopatch that is attached to each mouse's ear, we are starting to understand how a vaccine affects the immune cells in the skin. In the future we plan to apply this knowledge to improve vaccination in people.

Funded Activity Details

Start Date: 15-05-2010

End Date: 31-12-2012

Funding Scheme: Discovery Projects

Funding Amount: $825,000.00

Funder: Australian Research Council