Discovery Projects - Grant ID: DP1093195

Funding Activity

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Funded Activity Summary

New insights into mammalian gene transcription - the role of parafibromin. Increasing our knowledge of fundamental gene and protein interactions is imperative as we move into an era of targetted molecular therapies to treat disease. Cancer is at the forefront of these diseases with hope of improved treatments firmly based in understanding the basic cell biology of tumours. This proposal describes research into a protein called parafibromin. We propose that parafibromin acts in major pathways responsible for how a cell manages stress by regulating levels of proteins involved in the cellular stress response. Discoveries made during the course of this research will provide knowledge of gene and protein interactions that will be important in the future to develop anti-cancer therapies.

Funded Activity Details

Start Date: 03-06-2010

End Date: 31-12-2013

Funding Scheme: Discovery Projects

Funding Amount: $345,000.00

Funder: Australian Research Council