Discovery Projects - Grant ID: DP1093115

Funding Activity

Website
https://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP1093115

Funding Status
Closed

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

Defining mechanisms of action of novel alpha-conotoxins at nicotinic receptor-channels. Marine snails from the waters off the Australian coast produce an amazing variety of mini-proteins in their venoms called conotoxins that they use to capture prey. These conotoxins bind very specifically to receptors in our body associated with the transmission of nerve signals. We will use natural and synthetically modified conotoxins to selectively block particular types of neuronal 'receptors' to gain a greater understanding of how the nervous system functions. This knowledge will help in the design of new drugs to treat a variety of diseases and disorders. Essentially we will use a chemical armoury developed by the cone snail to design state-of-the-art mini-protein drugs.

Funded Activity Details

Start Date: 01-01-2010

End Date: 31-12-2015

Funding Scheme: Discovery Projects

Funding Amount: $1,400,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Basic Pharmacology | Biochemistry and Cell Biology | Biological And Medical Chemistry | Membrane Biology

ANZSRC Socio-Economic Objective (SEO)

Nervous system and disorders | Treatments (e.g. chemicals, antibiotics) | Biological sciences |

Other Keywords

Basic Pharmacology | Biochemistry and Cell Biology | Biological And Medical Chemistry | Biological sciences | Membrane Biology | Nervous system and disorders | Treatments (e.g. chemicals, antibiotics)

Related Links