Discovery Projects - Grant ID: DP1092675

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP1092675

Funding Status
Closed

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Funded Activity Summary

Systems therapeutics for metabolism: AMPK isoform specific drugs. Living cells have to maintain a steady balance between energy production and consumption in order to function properly. A key regulator of energy balance is an enzyme known as 5' AMP-activated protein kinase (AMPK), which regulates the burning and storage of fuels such as fat and sugars, in response to changes in energy demand. This project will provide a major advancement in our understanding of the regulation of AMPK at the molecular level, and lay the foundations for the development of more effective drugs to treat energy balance disorders such as obesity and Type 2 diabetes. Furthermore, this proposal will contribute to enriching Australia's international profile and competitiveness in this important area of research.

Funded Activity Details

Start Date: 01-01-2010

End Date: 31-12-2012

Funding Scheme: Discovery Projects

Funding Amount: $355,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Enzymes | Biochemistry and Cell Biology | Cell Metabolism | Protein Targeting And Signal Transduction

ANZSRC Socio-Economic Objective (SEO)

Health related to ageing | Preventive medicine | Treatments (e.g. chemicals, antibiotics) |

Other Keywords

Biochemistry and Cell Biology | Cell Metabolism | Enzymes | Health related to ageing | Preventive medicine | Protein Targeting And Signal Transduction | Treatments (e.g. chemicals, antibiotics)

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