Discovery Projects - Grant ID: DP1092582

Funding Activity

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Funded Activity Summary

Activation mechanisms of Cys-loop ion channel receptors. This proposal will employ a cutting edge approach to reveal fundamental new insights into the ways that proteins work. The information and technology developed here will broaden and strengthen Australia's research expertise across a number of basic scientific disciplines. The results will also have relevance to human health. Cys-loop ligand-gated receptors have an essential role in brain function and are targets for many therapies and drugs of abuse. New insights into how biological ligands and drugs affect ion channel structure and function may lead to novel therapeutic opportunities and improved drug structure predictions.

Funded Activity Details

Start Date: 01-01-2010

End Date: 31-12-2012

Funding Scheme: Discovery Projects

Funding Amount: $348,000.00

Funder: Australian Research Council