Discovery Projects - Grant ID: DP0988470

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0988470

Funding Status
Closed

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Funded Activity Summary

Cellular Responses to Adversity: Oxidative Stress and Protection Against Oxidative Damage. A deficiency in the protein haem oxygenase-1 causes severe biological consequences in animals and humans. These include decreased reproduction, retarded development, the inability of the body to handle iron, chronic inflammation and increased susceptibility to age-associated diseases. This study will determine how a deficiency of the protein alters cells at the level of genes, proteins and protein functions. By doing so, the project will illuminate how haem oxygenase-1 alters cell functions in a beneficial way. This information will eventually assist in preventing the serious disorders associated with deficiency of haem oxygenase-1. It will also provide the basis for novel treatments to slow down age-associated diseases.

Funded Activity Details

Start Date: 02-03-2009

End Date: 01-03-2012

Funding Scheme: Discovery Projects

Funding Amount: $304,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Enzymes | Biochemistry and Cell Biology | Cell Metabolism | Gene Expression

ANZSRC Socio-Economic Objective (SEO)

Health related to ageing | Preventive medicine | Biological sciences |

Other Keywords

Biochemistry and Cell Biology | Biological sciences | Cell Metabolism | Enzymes | Gene Expression | Health related to ageing | Preventive medicine

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