Discovery Projects - Grant ID: DP0988001

Funding Activity

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Funded Activity Summary

Engineering cartilage homeostasis in health and disease. Arthritis is a common, painful and often debilitating disease affecting 16% of the Australian population and costing this community $11 billion every year. It is not well understood why cartilage degenerates into joint disease, nor how it may be reversed - partly due to the large number of mechanisms involved. This project aims to overcome this complexity by developing a computational model of cartilage that can integrate the various mechanisms of cartilage degradation. New experiments will be used to validate the model and test predictions. The model developed will provide fundamental insights into what is required for the maintenance of healthy cartilage, and what happens in injury-induced degradation of cartilage.

Funded Activity Details

Start Date: 01-01-2009

End Date: 31-12-2012

Funding Scheme: Discovery Projects

Funding Amount: $230,000.00

Funder: Australian Research Council