Discovery Projects - Grant ID: DP0987045

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0987045

Funding Status
Closed

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Funded Activity Summary

Noncanonical epitope recognition by CD8+ T lymphocytes. This proposed research program will provide significant fundamental insight in the areas of immunology and vaccine design. Vaccines for many diseases remain elusive, and this project aims to improve our understanding of the precise regions within pathogens that are the targets for the killer T cells of the immune system. These regions, called epitopes, are likely to be key ingredients in many future vaccines. Although immunologists have gathered much information about such epitopes, recent studies have shown that some unexpected regions of pathogens are targets for killer T cells. This project will break new ground by utilising unbiased procedures to assess the relative contribution of these noncanonical epitopes to immunity.

Funded Activity Details

Start Date: 01-01-2009

End Date: 31-12-2012

Funding Scheme: Discovery Projects

Funding Amount: $449,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Immunological And Bioassay Methods | Microbiology | Cellular Interactions (Incl. Adhesion, Matrix, Cell Wall) | Virology

ANZSRC Socio-Economic Objective (SEO)

Immune system and allergy | Prevention—biologicals (e.g. vaccines) | Prevention—biologicals (e.g. vaccines) |

Other Keywords

Cellular Interactions (Incl. Adhesion, Matrix, Cell Wall) | Immune system and allergy | Immunological And Bioassay Methods | Microbiology | Prevention—biologicals (e.g. vaccines) | Virology

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