Discovery Projects - Grant ID: DP0987005

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0987005

Funding Status
Closed

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Funded Activity Summary

A novel role for SMG-1 protein kinase in stress granule formation and the stress response. Humans are constantly exposed to agents in the environment that threaten the integrity of their cells and increases the risk of cancer and other pathologies. Cells have developed repair mechanisms to cope with damage to their DNA and avoid long term effects. The emphasis in this application is to investigate the mechanisms by which stress affects the transcriptional machinery in the cell. A description of the processes involved will assist in understanding how specific disease states arise and will provide a means of devising compounds/drugs to assist the response to stress.

Funded Activity Details

Start Date: 01-01-2009

End Date: 31-12-2010

Funding Scheme: Discovery Projects

Funding Amount: $110,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry And Cell Biology Not Elsewhere Classified | Biochemistry and Cell Biology | Gene Expression | Protein Targeting And Signal Transduction

ANZSRC Socio-Economic Objective (SEO)

Health related to ageing | Biological sciences | Inherited diseases (incl. gene therapy) |

Other Keywords

Biochemistry And Cell Biology Not Elsewhere Classified | Biochemistry and Cell Biology | Biological sciences | Gene Expression | Health related to ageing | Inherited diseases (incl. gene therapy) | Protein Targeting And Signal Transduction

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