Discovery Projects - Grant ID: DP0986316

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0986316

Funding Status
Closed

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Funded Activity Summary

Electro-active and migratory peptides in lipid bilayers: NMR and biophysical studies. All living things are characterized by the separation of inner space from the surrounding medium by a self-assembling membrane. Selective entry and exit of water, ions and solutes is a defining feature of each type of cell. Some proteins sense the voltage difference across the cell membrane and open or close in response to voltage changes. Others, like bacterial toxins assemble in the membrane as pores, while other peptides migrate across the membrane piggy-backing their peptide cargo. The aim is to understand the molecular mechanisms in examples of these membrane-active peptides and proteins with a view to enabling rational intervention into their operation in situ in normal and disease states.

Funded Activity Details

Start Date: 20-05-2009

End Date: 31-12-2013

Funding Scheme: Discovery Projects

Funding Amount: $480,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Other Physical Sciences | Membrane Biology | Instruments And Techniques | Biophysics

ANZSRC Socio-Economic Objective (SEO)

Biological sciences | Chemical sciences | Physical sciences |

Other Keywords

Biological sciences | Biophysics | Chemical sciences | Instruments And Techniques | Membrane Biology | Other Physical Sciences | Physical sciences

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