Discovery Projects - Grant ID: DP0985963

Funding Activity

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Funded Activity Summary

Neural Copper Homeostasis: the role of the Alzheimer Amyloid-beta Precursor Protein. Alzheimer's disease (AD) is creating a growing burden upon Australian medical resources. Copper plays an important role in the development of AD, and drugs designed to adjust brain copper levels are being tested for AD treatment and show therapeutic benefits. This project will determine how copper is involved in AD so that more effective drugs can be developed. Focus will primarily be on copper-binding proteins central to AD, including amyloid-beta, and their role in AD development. Upon completion of this project, we expect to better understand neural copper metabolism in health and in AD pathology, with outcomes directly applicable to therapeutic AD intervention.

Funded Activity Details

Start Date: 01-01-2009

End Date: 31-12-2011

Funding Scheme: Discovery Projects

Funding Amount: $330,000.00

Funder: Australian Research Council