Discovery Projects - Grant ID: DP0985049

Funded Activity Summary

How does Fat cadherin control organ size in Drosophila, and cancer in humans? The primary function of Fat cadherin is to dictate the appropriate size of organs in developing animals. Deficiency in the fat gene results in vastly overgrown organs and can lead to the formation of cancer in humans. Our study will provide important insights into how the size of organs are controlled during development. Our research findings will have important implications for several aspects of human health and biology, and will increase our understanding of diseases that arise due to aberrant tissue growth, such as cancer. Our research findings will thus be of substantial national benefit, given that cancer is now the biggest cause of death in Australia, and that more than 88,000 Australians are diagnosed with cancer each year.

Funded Activity Details

Start Date: 01-01-2009

End Date: 31-12-2011

Funding Scheme: Discovery Projects

Funding Amount: $290,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Protein Targeting And Signal Transduction | Genetics | Cell Development (Incl. Cell Division And Apoptosis) | Genetic Development (Incl. Sex Determination)

ANZSRC Socio-Economic Objective (SEO)

Cancer and related disorders | Biological sciences | Organs, diseases and abnormal conditions not elsewhere classified |

Other Keywords

Biological sciences | Cancer and related disorders | Cell Development (Incl. Cell Division And Apoptosis) | Genetic Development (Incl. Sex Determination) | Genetics | Organs, diseases and abnormal conditions not elsewhere classified | Protein Targeting And Signal Transduction

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