Discovery Projects - Grant ID: DP0881263

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0881263

Funding Status
Closed

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Funded Activity Summary

Mitochondrial targeting of the DNA repair protein BARD1. This is a fundamental research project to address a novel localisation pattern of the nuclear DNA repair protein, BARD1. BARD1 gene mutations occur in a subset of breast/ovarian cancer patients, and improved insight into BARD1 regulation could enhance our understanding of this disease. There are over 13,000 new cases of breast/ovarian cancer each year with more than 3,300 deaths, making it a serious healthcare issue in Australia, and placing this project within Research Priority 2: Promoting and Maintaining Good Health. If successful this project will characterise the cellular transport route of BARD1 which could help in anti-cancer agent development.

Funded Activity Details

Start Date: 31-01-2008

End Date: 21-10-2010

Funding Scheme: Discovery Projects

Funding Amount: $264,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology | Cell Metabolism | Protein Targeting And Signal Transduction | Cell Development (Incl. Cell Division And Apoptosis)

ANZSRC Socio-Economic Objective (SEO)

Women’s health | Cancer and related disorders | Inherited diseases (incl. gene therapy) |

Other Keywords

Biochemistry and Cell Biology | Cancer and related disorders | Cell Development (Incl. Cell Division And Apoptosis) | Cell Metabolism | Inherited diseases (incl. gene therapy) | Protein Targeting And Signal Transduction | Women’s health

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