Discovery Projects - Grant ID: DP0881141

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0881141

Funding Status
Closed

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Funded Activity Summary

New Strategies for Monitoring DNA-Anticancer Drug Interactions. The highly successful cisplatin works by binding to DNA and partially unwinding or bending the DNA. As a consequence of the success if cisplatin, alternative anticancer drugs are being developed with reduced side effects for patients. One of the bottom necks in the development of alternative drugs is rapid screening of the efficacy on new leads. The proposed research will develop new technologies for monitoring DNA-drug binding, DNA damage and DNA repair using novel DNA biosensors. the novelty of the biosensor technology will be to use the modulation of charge transfer through DNA as a method for determining the structural changes that occur in DNA due to these events occurring.

Funded Activity Details

Start Date: 01-01-2008

End Date: 09-12-2008

Funding Scheme: Discovery Projects

Funding Amount: $320,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Analytical Chemistry | Nanotechnology | Sensor (Chemical And Bio-) Technology | Electroanalytical Chemistry

ANZSRC Socio-Economic Objective (SEO)

Cancer and related disorders | Biological sciences | Chemical sciences |

Other Keywords

Analytical Chemistry | Biological sciences | Cancer and related disorders | Chemical sciences | Electroanalytical Chemistry | Nanotechnology | Sensor (Chemical And Bio-) Technology

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