Discovery Projects - Grant ID: DP0881116

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0881116

Funding Status
Closed

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Funded Activity Summary

Understanding and Inhibiting the P450 CYP24 enzyme, a target for cancer chemotherapeutics. This project falls within the National Research Priority of Promoting and Maintaining Good Health in the category of ageing well and productively. CYP24 inhibition provides a particular target for breast and prostate cancer which are the second leading cause of death in women and men, respectively. The proposed research will result in the production of CYP24 inhibitors that will be assessed in vivo at the Hanson Institute in Adelaide as potential anti-cancer drugs. Finally, there is a significant benefit in technology transfer to Australia from our collaborators in the USA in the field of computer aided inhibitor design.

Funded Activity Details

Start Date: 01-01-2008

End Date: 31-12-2010

Funding Scheme: Discovery Projects

Funding Amount: $245,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Enzymes | Bioinorganic Chemistry | Biochemistry and Cell Biology | Biological And Medical Chemistry |

ANZSRC Socio-Economic Objective (SEO)

Health related to ageing | Treatments (e.g. chemicals, antibiotics) | Chemical sciences

Other Keywords

Biochemistry and Cell Biology | Bioinorganic Chemistry | Biological And Medical Chemistry | Chemical sciences | Enzymes | Health related to ageing | Treatments (e.g. chemicals, antibiotics)

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