Discovery Projects - Grant ID: DP0880844

Funding Activity

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Funded Activity Summary

Molecular dissection of the effects of alpha-actinin-3 deficiency on normal variation in skeletal muscle function. We will study the mechanisms by which a common genetic variant influences muscle bulk, muscle strength and the metabolic efficiency of muscle in the general population. Common genetic variants that influence skeletal muscle function have major potential public health implications as they are likely to influence individuals' response to exercise and diet, and to contribute to susceptibility to common diseases such as obesity, diabetes, and the loss of muscle strength in the elderly. In addition, the identification of genetic factors that influence muscle bulk in vertebrates has implications for breeding programs in sheep and cattle and may provide commercial benefit to the livestock industry.

Funded Activity Details

Start Date: 19-03-2008

End Date: 17-03-2012

Funding Scheme: Discovery Projects

Funding Amount: $357,564.00

Funder: Australian Research Council