Discovery Projects - Grant ID: DP0880027

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0880027

Funding Status
Closed

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Funded Activity Summary

The role of gamma glutamyl cyclotransferase in glutathione homeostasis. The aim of this study is to understand the structure and function of gamma-glutamyl cyclotransferase (GGCT) and its role in glutathione synthesis and turnover. Glutathione is essential for life and serves multiple biological functions protecting against oxidative stress, and aiding in the detoxification and excretion of foreign chemicals. This study will explore a new approach to changing intracellular glutathione concentrations that has wide applications in the treatment of inherited enzyme deficiencies, cancer and the development of herbicide resistant crop plants. The study will also contribute to the training of scientists for the future development of the Australian biotechnology industry

Funded Activity Details

Start Date: 01-01-2008

End Date: 31-12-2011

Funding Scheme: Discovery Projects

Funding Amount: $135,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medicinal and Biomolecular Chemistry | Biological And Medical Chemistry |

ANZSRC Socio-Economic Objective (SEO)

Treatments (e.g. chemicals, antibiotics) | Organs, diseases and abnormal conditions not elsewhere classified | Field crops not elsewhere classified

Other Keywords

Biological And Medical Chemistry | Field crops not elsewhere classified | Medicinal and Biomolecular Chemistry | Organs, diseases and abnormal conditions not elsewhere classified | Treatments (e.g. chemicals, antibiotics)

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