Discovery Projects - Grant ID: DP0879414

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0879414

Funding Status
Closed

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Funded Activity Summary

Development of a prime-boost anti-cancer vaccine. New vaccination strategies are urgently needed for a variety of diseases, including cancer. The problem with cancer vaccines is that it is difficult to trigger a response to a self protein. We propose that a prime-boost vaccination, using yellow fever virus and modified vaccinia virus ankara, could create very strong responses against tumor antigens. This approach can be patented and can revive that field of tumor vaccination, which is currently restrained by the difficulty of breaking immunological tolerance. We envisage the construction of a anti-cancer vaccine vector with obvious market potential. An exciting prospect is that this approach could be used as a prophylactic vaccine and possibly also as a therapeutic vaccine.

Funded Activity Details

Start Date: 08-06-2008

End Date: 31-12-2011

Funding Scheme: Discovery Projects

Funding Amount: $231,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Other Medical and Health Sciences | Medical Biotechnology | Therapies And Therapeutic Technology | Cellular Immunology

ANZSRC Socio-Economic Objective (SEO)

Prevention—biologicals (e.g. vaccines) | Treatments (e.g. chemicals, antibiotics) | Cancer and related disorders |

Other Keywords

Cancer and related disorders | Cellular Immunology | Medical Biotechnology | Other Medical and Health Sciences | Prevention—biologicals (e.g. vaccines) | Therapies And Therapeutic Technology | Treatments (e.g. chemicals, antibiotics)

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