Discovery Projects - Grant ID: DP0879121

Funding Activity

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Funded Activity Summary

A novel approach to fighting fungal infections: targeted disruption of hydrophobin monolayers. Fungal infestations of important crops such as cotton cause large economic losses to Australian agriculture while in the medical sector, fungal infections are responsible for high levels of mortality in immunocompromised patients. Our research will provide a new approach to fighting fungal infections by targeting the hydrophobin proteins, which form a robust coating on fungal aerial structures, such as spores. This layer is critical for fungal growth and reproduction and confers water resistance and tolerance to harsh conditions. Our work seeks to develop reagents that can specifically block regions on the protein that are responsible for forming this coating.

Funded Activity Details

Start Date: 18-01-2008

End Date: 31-12-2010

Funding Scheme: Discovery Projects

Funding Amount: $244,251.00

Funder: Australian Research Council