Discovery Projects - Grant ID: DP0878081

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0878081

Funding Status
Closed

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Funded Activity Summary

A role for Cited2, Transforming Growth Factor-beta and matrix metaloproteinases in trophoblast invasion and placenta formation. The placenta is essential for the growth and development of the fetus, and if it fails to form correctly during pregnancy, it can have dramatic effects that can result death in utero, or adult onset diseases. Our research aims to understand how one protein functions in placenta formation. We will also investigate how this protein works at the molecular level in a process that enables single cells to respond to molecules sent from a distance by other cells (TGF-beta signalling). This process is also very important for a host of other biological processes relevant to human health, including cancer.

Funded Activity Details

Start Date: 01-01-2008

End Date: 31-12-2010

Funding Scheme: Discovery Projects

Funding Amount: $252,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Protein Targeting And Signal Transduction | Fetal Development And Medicine | Genetics | Genetic Development (Incl. Sex Determination)

ANZSRC Socio-Economic Objective (SEO)

Biological sciences | Organs, diseases and abnormal conditions not elsewhere classified |

Other Keywords

Biological sciences | Fetal Development And Medicine | Genetic Development (Incl. Sex Determination) | Genetics | Organs, diseases and abnormal conditions not elsewhere classified | Protein Targeting And Signal Transduction

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