Discovery Projects - Grant ID: DP0877315

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0877315

Funding Status
Closed

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Funded Activity Summary

Bacterial monooxygenases as new biocatalysts. Using enzymes for synthesis of new pharmaceuticals is of increasing importance. Monooxygenases are particularly interesting because of their capacity to perform chemically difficult reactions thus increasing potential to make new pharmaceuticals. We have shown that an enormous pool of diverse and novel monooxygenases exists in naturally occurring bacteria. These enzymes are naturally important in pollutant degradation and regulating the emissions of greenhouse gases. We will develop these enzymes for biotechnology by characterizing structural features that influence catalytic properties relevant to challenges in pharmaceutical synthesis. The outcomes will enable their engineering for specific applications in synthesis of new drugs.

Funded Activity Details

Start Date: 10-03-2008

End Date: 31-12-2010

Funding Scheme: Discovery Projects

Funding Amount: $240,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Agricultural Biotechnology | Genetic Engineering And Enzyme Technology | Microbiology Not Elsewhere Classified | Characterisation Of Macromolecules

ANZSRC Socio-Economic Objective (SEO)

Organic industrial chemicals not classified elsewhere | Treatments (e.g. chemicals, antibiotics) | Biological sciences |

Other Keywords

Agricultural Biotechnology | Biological sciences | Characterisation Of Macromolecules | Genetic Engineering And Enzyme Technology | Microbiology Not Elsewhere Classified | Organic industrial chemicals not classified elsewhere | Treatments (e.g. chemicals, antibiotics)

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